• Detection of DHCMT long-term metabolite glucuronides with LC-MSMS as an alternative approach to conventional GC-MSMS analysis 

      Göschl, Lorenz; Gmeiner, Günter; Gärtner, Peter; Steinacher, Michael; Forsdahl, Guro (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-02-17)
      Dehydrochloromethyltestosterone (DHCMT) is one of the most detected illicit used anabolic–androgenic steroids in professional sports. Therefore, a fast and accurate analysis of this substance is of great importance for a constructive fight against doping abuse. The conventional method for the analysis of this drug, GC-MSMS, is very sensitive and selective but also very time- and resource-consuming. ...
    • Development and validation of a simple online-SPE method coupled to high-resolution mass spectrometry for the analysis of stanozolol-N-glucuronides in urine samples 

      Göschl, Lorenz; Gmeiner, Günter; Enev, Valentin S; Kratena, Nicolas; Gärtner, Peter; Forsdahl, Guro (Journal article; Tidsskriftartikkel; Peer reviewed, 2020-04-17)
      Stanozolol is still the most commonly used illicit anabolic‐androgenic steroid (AAS) in professional sports. Therefore, accurate and fast analysis and long detection windows are of great interest in the field of antidoping analysis. In this work, a very simple, fast, and highly sensitive online solid‐phase extraction method coupled with liquid chromatography–high‐resolution tandem mass spectrometry ...
    • Quantification of endogenous steroid sulfates and glucuronides in human urine after intramuscular administration of testosterone esters 

      Forsdahl, Guro; Zanitzer, Katharina; Erceg, Damir; Gmeiner, Günter (Journal article; Tidsskriftartikkel; Peer reviewed, 2020-02-22)
      For an effective detection of doping with pseudo-endogenous anabolic steroids, the urinary steroid profile is of high value. In this work, the aim was to investigate steroid metabolism disruption after exogenous intramuscular administration of different testosterone esters. The investigation focused on both sulfo – and glucoro conjugated androgens. A single intramuscular injection of either 1000 mg ...
    • Stanozolol-N-glucuronide metabolites in human urine samples as suitable targets in terms of routine anti-doping analysis 

      Göschl, Lorenz; Gmeiner, Günter; Gärtner, Peter; Stadler, Georg; Enev, Valentin; Thevis, Mario; Schänzer, Wilhelm; Guddat, Sven; Forsdahl, Guro (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-06-05)
      The exogenous anabolic-androgenic steroid (AAS) stanozolol stays one of the most detected substances in professional sports. Its detection is a fundamental part of doping analysis, and the analysis of this steroid has been intensively investigated for a long time. This contribution to the detection of stanozolol doping describes for the first time the unambiguous proof for the existence of ...